Best Strains for Pain

BY: LEE Burgess


Cannabis has been used for pain relief for a really long time. As more and more studies come out scientists are able to figure out some of the reasons why cannabis is so effective for treating pain and inflammation. A study from 2014 showed that beta-caryophyllene directly interacted with CB2 receptors and was shown to help reduce inflammatory and neuropathic pain. This is really interesting because beta-caryophyllene is unlike any other terpene due to the fact that it is the only one that has the ability to directly activate a cannabinoid receptor, especially CB2 receptors.

Beta-caryophyllene or BCP, can be found in aromatic oils like rosemary and clove oil, and in nature it’s most commonly found in hops, cloves, black pepper, oregano, cinnamon, and basil. Strains that are high in BCP usually have a spicy and musky smell, and some are also known to have a funky profile. Many may carry a strong diesel or fuel smell that makes you nose tingle, similar to taking a whiff of pepper.

Some strains that routinely test high in beta-caryophyllene are:
  • GSC
  • ACDC
  • Sour Diesel
  • Gelato
  • The White
  • Master Kush
  • Original Glue

For more information, we recommend the following links…

What is caryophyllene and what does this cannabis terpene do?

The cannabinoid CB₂ receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain.

Wachter K. Navigating cannabis options for chronic pain. Practical pain management.

Cannabinoids in the management of difficult to treat pain.